Policaptil Gel Retard® reduces body weight and improves insulin sensitivity in obese subjects

Main Article Content

Giorgia Centorame
Maria Pompea Antonia Baldassarre
Giulia Di Dalmazi
Francesca Gambacorta
Fabrizio Febo
Agostino Consoli
Gloria Formoso

Keywords

caloric intake, dietary fiber, glycemic index, Mediterranean diet, obesity

Abstract

Policaptil Gel Retard® (PGR), a natural fiber-based molecule, has been shown to prevent weight gain and ameliorate insulin-resistance indices in obese children and adolescents. The aim of this study was to compare the effects of 12 weeks of low calories and low glycemic index (LC-LGI) diet associated or not with the intake of PGR on anthropometric, bioimpedance, and metabolic parameters. Data from 20 obese adult subjects (10 per group) were analyzed. An LC-LGI diet with or without PGR intake reduced weight, BMI, and waist circumference. PGR intake elicited a reduction in fasting plasma insulin and insulin resistance index together with an improvement in insulin sensitivity.

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